How long does it take for Orlistat to work?

In this article, we’ll look into how long it typically takes for Orlistat to start working and how you can maximise its effectiveness. We’ll explore the factors that influence it, tips for achieving the best outcomes and what steps to take if Orlistat doesn’t deliver the results you were hoping for. Whether you’re considering Orlistat for the first time or looking for ways to enhance its impact, this guide will provide the insights you need to make informed decisions. Always consult with your healthcare provider before starting any weight loss medication.

Key Takeaways

Here are the five biggest takeaways from this article about how long it takes Orlistat to work:

• Orlistat begins working within 1–2 days by reducing fat absorption in the digestive system. However, visible weight loss typically takes about two weeks.

• Gradual and sustainable weight loss of 1–2 pounds per week is the healthiest approach when using Orlistat.

• Orlistat works best when paired with a balanced diet rich in fibre, lean proteins, and healthy fats. Avoiding high-fat, processed foods and maintaining regular exercise (150 minutes per week) are essential to maximise results.

• By three months, you should aim to have lost at least 5% of your body weight. If this milestone isn’t reached, Orlistat may not be the right treatment for you, and alternative options should be considered.

• If Orlistat isn’t effective, consult your doctor about other treatments, such as Saxenda, Wegovy, or Mounjaro.

How long does it usually take for Orlistat to work?

Orlistat begins working within 1 to 2 days of use by blocking the absorption of dietary fat in the digestive system. This means that your body absorbs fewer calories from the fat in your meals. While the medication acts quickly, visible weight loss tends to take a bit longer. Most people notice weight loss within two weeks of starting Orlistat, provided it is combined with a calorie-controlled diet and regular physical activity.

Early changes may not always be noticeable on the scale. Still, over the first few weeks, the combination of reduced fat absorption and healthier lifestyle habits can lead to steady and sustainable weight loss. This early progress is an encouraging sign that the medication is working and can provide the motivation you need to stay consistent.

Orlistat Weight Loss Timeline

Below is a table outlining the typical timeline of results with Orlistat:

How can you get the best results from using Orlistat?

To achieve the best results with Orlistat, it’s essential to use the medication alongside meaningful lifestyle changes [1]. Orlistat is most effective when you eat a balanced diet rich in fibre, lean protein and healthy fats. Avoid high-fat, sugary, and heavily processed foods, as these can not only counteract your progress but may also lead to unpleasant side effects. Focus on portion control and aim for meals that include plenty of vegetables, whole grains, and nutrient-dense foods.

As well as consuming a healthy diet, getting plenty of exercise is also key. Aim for at least 150 minutes of moderate exercise per week. This can include walking, cycling, or swimming. Staying hydrated is also important. Drink 6–8 glasses of water daily to support your overall health and weight loss.

Cutting back on alcohol, reducing your intake of junk food and prioritising home-cooked meals over takeaways can help you stay on track. Gradual weight loss of 1–2 pounds per week is not only healthier but also more sustainable in the long run.

If your weight loss halts or if you feel Orlistat isn’t working for you, speak with your healthcare provider. 

What can I do if Orlistat doesn't work as effectively as I hoped?

If Orlistat doesn’t deliver the results you were hoping for, the first and most important step is to speak with your doctor. They can assess your progress, evaluate your overall health and determine whether Orlistat is the right medication for you. In some cases, they may recommend adjusting your dosage, re-evaluating your diet and exercise plan, or exploring other weight loss treatments.

Your doctor might suggest alternative prescription options like Saxenda, Mounjaro or Wegovy. These medications work differently from Orlistat, focusing on appetite regulation and blood sugar control as opposed to fat absorption. In the same way as Orlistat, these treatments are most effective when combined with a balanced diet and regular physical activity.

You may also wish to seek support from a dietitian or weight loss specialist who can provide tailored advice to help overcome challenges and improve results.

Sources

[1] How to Lose Weight: Simple Tips For Your Weight Loss Journey - UK Meds

Further Reading

Orlistat Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD

Obesity - Treatment - NHS

Orlistat (Weight Loss Medicine): Uses and Side-Effects - Patient